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Research Interest

Research Interest

Chemo-enzymatic synthesis of glycoconjugates

  • The synthesis of O-glycans

O-glycans play vital role in human body, due to the limited access to those glycans, the function of those glycans still uncover. In our group, we are using chemo-enzymatic approach to access different O-glycans, such as O-GalNAc and O-Man glycans. The combination of chemcial method and enzymatic method facilitated the obtain of those functional glycans.The synthesis of O-glycans

  • The obtain of glycosaminoglycans (GAGs)

We are using different approach to get glycosaminoglycans, such as hyaluronan (HA), chondroitin sulfate (CS), and dermatan sulfate (DS).